TSIKINIS ANIVAS

{slider PROFILE}

• Breast surgery, Oncoplastic and Reconstructive Breast Surgeon / Metropolitan General Associate.
• PhD Title from the Medical School of the National and Kapodistrian University of Athens.
• Upon receiving the specialty title of Surgeon, until my departure from the "Elena Venizelos" Hospital, my full and exclusive employment was the subject of the breast, with participation in all the scientific activities of the Breast Surgery Clinic, such as abroad doctor's office, surgeries, either as a surgeon or as a partner trainer, as well as research programs of my department or in collaboration with other oncology departments of other Hospitals. I have participated in variety of seminars and conferences with research papers, participation in round tables and announcements in Greece and Abroad as well as publications in Greek and foreign magazines.

{slider EDUCATION & ACADEMIC TITLES}

• Military Service in the National Guard of Cyprus (1969 - 1970).
• Degree in Medicine, of the Department of the Medical School of the National and Kapodistrian University of Athens (March 1980) (No. 14245 / 25-3-1980).
• Rural Medical service, Kilkis General Hospital (July 26, 1980 to September 10, 1981).
• Permission to practice medicine. Decision TY 1682 / 18-5-1981, Prefecture of Kilkis.
• Specialty Training post. Resident of General Surgery assistant of the First Surgery Clinic of the General State Hospital of Athens (Director: SA Professor J. Poulantzas) - (September 22, 1981 - May 31, 1985).
• Title of Medical Specialty of Surgery (CCT). Professional degree title. Region of Attica, General Directorate of Public Health and Social Care, Greece. Protocol Number 10866 / 15-7-1985.
• Doctoral dissertation from the Medical School of the University of Athens on: Splenic implants for the maintenance of splenic functions after splenectomy. Protocol Number 4090/1022 / 28-6-1990.

{slider PROFESSIONAL EXPERIENCE}

• Specialized surgeon in the position of salaried assistant of the Surgery Clinic of the "MARIKA ELIADI" Maternity Hospital (Breast Center - Breast Surgery Clinic) (Director: Dr. St. Vassilaros), (June 25, 1985 - February 19, 1987).
• Specialized surgeon in the position of Curator B΄, Department of Surgery of the branch of NHS of the Obstetrics-Gynecology Center of Athens "ELENA VENIZELOS" (Breast Center - Breast Surgery Clinic) (Director: SA Professor St. Vassilaros), (February 19, 1987 - November 24, 1997).
• Specialized surgeon in the position of Curator B΄, Department of Surgery of the branch of NHS doctors from November 1997 to November 24, 1998 of the Regional General Hospital - Maternity Hospital "ELENA VENIZELOS", until April 4, 2006 (Breast Center - Breast Surgery Clinic) (Scientific Officer: Dr. Ioannis Papadiamantis).
• Specialized surgeon in the position of Curator A΄, Department of Surgery of the branch of NHS of the Regional General Hospital - Maternity Hospital "ELENA VENIZELOS", from November 24, 1998 to April 4, 2006 (Breast Center - Breast Surgery Clinic) (Scientific Officer: Dr. Ioannis Papadiamantis).
• Specialized surgeon in the position of Deputy Director, Department of Surgery of the branch of NHS of the Regional General Hospital - Maternity Hospital "ELENA VENIZELOS", from April 4, 2006 to December 31, 2007 (Breast Center - Breast Surgery Clinic) (Scientific Officer: Dr. Ioannis Papadiamantis).
• From January 1, 2008, I served as Scientific and Administrative Officer of the 1st Surgical Department (Breast Center - Breast Surgery Clinic), until September 4, 2009.
• From September 4, 2009 and after crises, I served as Director of the First Surgical Department (Breast Center - Breast Surgery Clinic) until my departure on December 31, 2018.
• During my entire service as a specialist surgeon at the General State Hospital of Athens (from September 1981 to May 1985) I actively participated in the scientific activities of the Breast Center - Breast Surgery Clinic of "Elena Venizelos” Hospital, taking part in the research program of the department. And from my service, as Curator B, Curator A and as Deputy Director of the department but also as the responsible Director of the department, I took part in all its scientific activities, such as the outpatient clinic, surgeries, either as a surgeon or as a partner trainer, as well as the department's research program or in collaboration with other oncology departments of other hospitals.

{slider MEMBERSHIP IN SOCIETIES & EDITORIAL BOARDS}

• Member of the Hellenic Cancer Society.
• Member of the Hellenic Society of Liver-Bowel-Pancreatic Surgeons.
• Member of the Hellenic Surgical Society.
• Member of the Hellenic Society of Mastology.
• Founding member of the Hellenic Cancer Action Society.
• Member of the Hellenic Breast Surgery Society.

{slider RESEARCH PROGRAMS}

• Participation in seminars and conferences in Greece and abroad, in collaboration with Nursing and Educational Institutions of Greece and abroad.
• Participation in research programs and protocols in collaboration with Nursing and Educational Institutions of Greece and abroad.
• As a member of N.E.L.E. of Attica I presented five (5) lectures on cancer - "prevention - diagnosis - treatment" -, in three municipal districts of the Municipality of Athens, in the spiritual center of the Municipality of N. Chalkidona Attica and in Ekali, during the year 1987.
• Participation of seminar and conference work, in Greece and abroad, with the subject being mostly problems and medical conditions of the breast.
• Upon receiving the specialty title of Surgery, until my departure from the "Elena Venizelos" Hospital, my full and exclusive employment was the subject of the breast, with participation in all the scientific activities of the Breast Surgery Clinic, such as abroad doctor's office, surgeries, either as a surgeon or as a partner trainer, as well as the research program of the department or in collaboration with other oncology departments of other hospitals, as well as in a variety of seminars and conferences with papers, participation in round tables and announcements in Greece and abroad as well as publications in Greek and foreign magazines.
• I participated with other fellow doctors in the Hellenic Collaborating Breast Team (ESOMPS), (AHEPA Hospital of Thessaloniki, METAXA Piraeus Hospital, Breast Center of “ELENA VENIZELOS” Hospital, IKA Breast Clinic of Athens, Oncology Hospital “Agioi Anargyroi” Kifisia), at planning, treating and monitoring groups of breast cancer patients. (Preoperative chemotherapy in women with stage II and III breast cancer).
• Cooperation with EORTC (European Organization for Research on Treatment of Cancer) in the protocol No. 10792 for locally advanced breast cancer.
• Participation with other colleagues in the "Hellenic Collaborating Oncology Group for Breast Cancer" (A. Polychronis, G. Foutzilas, P. Kosmidis, D. Scarlos, N. Pavlidis, K. Gennatas, St. Tsiliakos, C. Semoglou, D. , E. Fachatidis, A. Katsorhis, C. Konstantaras, D. Chainoglou, I. Papadiamantis, A. Tsikkinis, T. Giannakakis, N. Kalogeropoulos, N. Zampoglou, St. Vassilaros) whose purpose was planning, treatment and monitoring of groups of patients with stage II breast cancer.
• Participation with other colleagues in the clinical trial test protocol of the M - FP (Mannan - Muc 1 Fusion Protein) vaccine at the Austrian Research Institute "The Austin Research" in post-menopausal women with stage II breast cancer, the results of which are published in the journal Cancer Research.
• Participation in research programs for the investigation of the cause of breast cancer, carried out by the Laboratory of Hygiene and Epidemiology of the University of Athens Medical School in collaboration with the Breast Center of the "Elena Venizelos" Hospital, the last of which was recently completed and is expected to be published in a foreign magazine.
• Participation with other colleagues in the CARIATIDE study which was conducted in more than 350 centers, in 18 countries around the world, including Greece, in which the impact of the use of educational material in shaping patients at greater risk of non-compliance is assessed in the treatment and understanding of the factors that determine such behavior.
• Participation with other colleagues in the COPA study, a study by the Hellenic Breast Surgery Society entitled "Prospective COMPETITION study, to monitor the coagulation parameters in postmenopausal patients with surgery for five-year breast cancer surgery, which they receive established practice ".
• Participation with other colleagues in the ADVICE study entitled: “Aromatase inhibitors as a treatment for women with early breast cancer positive for estrogen receptors (ER) and cognitive function. Current experience in real clinical conditions in Greece.

{slider DISTINCTIONS & AWARDS}

• I received a commemorative mention in support of the implementation of the International Voluntary Breast Cancer Support Program "Reach to Recovery", implemented by the Panhellenic Association of Women with Breast Cancer "Alma Zois".

{slider PUBLICATIONS}

• Announcements of at least 90 works such as speeches or posted announcements in Greek and Foreign conferences.
• Publishing in Greek and foreign magazines

1) Compound injuries of the liver.
Papastamatiou L., Kalokairinos E., Tsikkinis A., Poulantzas I.
Medical Inspection of the Armed Forces 18: 35 - 37, 1984.

2) Maintaining the function of the spleen with splenic implants after splenectomy.
Papastamatiou L., Antoniadis I., Tsikkinis A., Poulantzas I.
Hellenic Surgery 56: 51 - 55, 1984.

3) Estrogen and Progesterone Receptors in human Breast cancer, in correlation with histologic type and other clinico histological parameters.
Lariou C., Karaiossifidi H., Papadiamantis I. and Tsikkinis A.
Path. Res. Practice. Vol.182 No.4 pp.453 - 584, August 1987.

4) Elevated Expression of A P - 1 Activity in Human Breast Tumors as Compared to Normal Adjacent Tissue.
S. Linardopoulos, A. Malliri, A. Pintzas, S. Vassilaros, A. Tsikkinis and D.A. Spandidos.
Anticancer Research 10: 1711 - 1714, (2285246), 1990.

5) Expression of Ras Rb1 and p53 Proteins in Human Breast Cancer.
D.A. Spandidos, H. Karaiossifidi, A. Malliri, S. Linardopoulos, S. Vassilaros, A. Tsikkinis and J. K. Field.
Anticancer Research 12: 81 - 90, (1567185), 1992.

6) Flow Cytometry and Breast Cancer: Prognostic Significance for Relapse Free Survival.
H. Karaiossifidi, A. Potamianou, J. Papadiamantis H. Arvaniti, A. Tsikkinis, S. Vassilaros, E. Kouri.
Journal of the European Society for Analytical Cellular Pathology, ACPAER 4 (3): 179 - 180, 1992.

7) No Adjuvant Tamoxifen Versus Adjuvant Tamoxifen in Node negative postmenopausal breast cancer patients. A randomized study - Preliminary results.
A. Potamianou, N. Kalogeropoulos, E. Karaveli, A. Tsikkinis, J. Papadiamantis, A. Polychronis, S. Tsiliakos, S. Vassilaros.
HSBCR First international congress. p. 262 abst. Pc27. 1993

8) Pre-operative chemotherapy in Locally Advanced Breast Cancer.
J. Papadiamantis, N. Malamos and A. Tsikkinis.
Recent Advances in Chemotherapy "American Society for Microbiology" p. 977, 1994.

9) Genetic Alterations in erbB-1, erbB-2 and erbB-3 gene in breast cancer.
M. Chatzipanagiotou, V. Zoumpourlis, A. Kotsinas, M. Ergazaki, E. Gontikakis, A. Tsikkinis, S. Vassilaros and D.A. Spandidos.
Hellenic Biochemical and Biophysical Society, Newsletter 40, April 1996.

10) The conservative treatment of intrauterine breast cancer: Clinical-pathological study, with follow-up.
Manidakis L, Karaiosifidis E, Pallis L, Tsikkinis A, Kouri E, Vassilaros S.
Greek Oncology - volume 32 - issue 2 April-June 1996.

11) Microsatellite instability and loss of Heterozygosity in Primary Breast Tumors.
G. Sourvinos, H. Kiaris, A. Tsikkinis, S. Vassilaros, D.A. Spandidos.
Tumor Biology 1997; 18: 157-166, (9143412).

12) A randomized clinical trial of primary chemotherapy (PC) with Taxol + Epirubicin (TE) vs 5-FU + Epirubicin + Cyclophosphamide (FEC) in stage IIIA breast cancer: A preliminary report.

J. Papadiamantis, N. Malamos, M. Antonopoulos, A. Tsikkinis, H. Kosmas, S. Vassilaros.
The European Journal of Cancer, Vol.34 - suppl.5: S14, 1998.

13) Prospective randomized study of Neoadjuvant chemotherapy (NACT) with Paclitaxel / Epirubicin (PE) vs Fluorouracil / Epirubicin / Cyclophosphamide (FEC) in operable stage II-IIIA breast cancer (BC).

N. Malamos, C. Kosmas, M. Antonopoulos, A. Tsikkinis, L. Pallis, E. Kouri, J. Papadiamantis, S. Vassilaros.
Annals of Oncology 1998, vol. 9 - suppl.4, 1998.

14) The Application of color Flow Studies in the U / S examination of the breast, Comparison of color Doppler and Power Doppler (a work in progress).

P. Hadjilira, S. Lyra, Hel. Andipa, E. Kyriakopoulos, Ann. Tsikkinis, V. Georgountzos, M. Tsouroulas, G. Tritakis, K. Stringaris.
HSBCR, the state of the art in 1999, ed. Synedron, pp.79-82, 1999.

15) Stereotactic needle localization of non-palpable lesions of the breast.
M. Kousaris, B. Venizelos, P. Malakasis, A. Tsikkinis, A. Tsibanis, S. Vassilaros.
HSBCR, the state of the art in 1999, ed. Synedron, pp.108-109, 1999.

16) Correlation between histologic grading and DNA ploidy and tumor markers in fine needle aspiration of ductal breast carcinomas.
N. Margari, I. Papadiamantis, L. Pallis, A. Tsikkinis, H. Margari, K. Kampitsis, E. Kouri, M. Gavriil, P. Karakitsos.

Cytopathology (official journal of the British Society for Clinical Cytology)
Vol. 15 (Suppl. 2), 1-13, 2004.

17) Pilot phase III immunotherapy study in early stage breast cancer patients using oxidized mannan-MUC1 (ISRCTN 71711835).

Apostolopoulos V., Pietersz GA., Tsimpanis A., Tsikkinis A., Drakaki H., Loveland BE., Piddlesden S.J., Plebanski M., Pouniotis D.S., Alexis M.N., McKenzie I.F., Vassilaros St.
Breast Cancer Research 2006 Jun, 15; 8 (3) .. R27 (16776849).

18) Diet and expression of estrogen alpha and progesterone receptors in the normal mammary gland ( DOI 10.1007/s 10552-008-9269-8 ).

Pagona Lagiou, Evangelia Samoli, Areti Lagiou, Cristina Georgila, Pantelina Zourma, Anastasia Barbouni, George Gkiokas, Dorothy Vassilarou, Annivas Tsikkinis, Constantinos Sfikas, Constantine E. Sekeris, Chung-Cheng Hsief, Hans- Olov Adami, Dimitrios Trichopoulos.
Cancer Causes Control (2009) 20:601-607- Springer Science + Business Media B.V. 2008 ( DOI 10.1007/s 10552-008-9269-8 ).

19) Diet and expression of estrogen alpha and progesterone receptors in malignant mammary gland.
Areti Lagiou, Evangelia Samoli, Cristina Georgila, Pantelina Zourma, Anastasia Barbouni, Dorothy Vassilarou, Annivas Tsikkinis, Constantine E. Sekeris, Dimitrios Trichopoulos, Pagona Lagiou.

Nutrition and Cancer, 63 (1), 65-72, 19/09/2011, 0163-5581 print/ 1532-7914 on line, Doi: 10.1080/01635581.2010.516872

20) A comparison of hormonal profiles between breast cancer and benign breast disease: a case – control study.

P. Lagiou, E Samoli, A. Lagiou, P. Zourna, A. Barbouni, C. Georgila, A. Tsikkinis, D. Vassilarou, P. Minaki, C. Sfikas, E. Spanos and D. Trichopoulos.
Annals of Oncology, May 30, 2013 (00: 1-7, 2013, doi: 10.1093/annonc/mdt207).

21) Up to 15-years clinical follow-up of a pilot Phase III immunotherapy study in stage II breast cancer patients using oxidized mannan-MUC1
Stamatis Vassilaros, Anastasios Tsibanis, Annivas Tsikkinis, Geoffrey A Pietersz, Ian FC McKenzie & Vasso Apostolopoulos.

Future Medicine – Immunotherapy, November 2013, Vol. 5, No. 11, Pages 1177-1182, DOI 10.2217/imt.13.126 ( doi 10.2217/imt.13.126 ).

22) Impact and risk factors for lymphedema after axillary clearance for breast cancer.
P. Daskalakis, I. Flessas, E. Karopoulou, D. Korfias, I Papanagiotou, V. Kalles, T. Mariolis-Sapsakos, A. Tsikkinis.

(10th European Breast Cancer Conference, Amsterdam, 9-11 March 2016)
European Journal of Cancer, Volume 57 Supplement 2, April 20

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